Kathy is the alcoholic and smoking addicted mother of the young, but mature teenager Lizzy. They live together since Kathy's husband Roy left her, and she neglects her daughter. Kathy is supposed to drive Lizzy to her father's home in the morning, but she sleeps until late afternoon and they have to travel during a rainy night. While driving through a lonely road through the woods, Kathy hits a wolf that breaks her car, leaving them stranded on the empty road. They call 911 and while waiting for the tow truck and an ambulance, the wolf disappears from the road. When the tow truck arrives, the mechanic Jesse tells that he needs to fix the axle and an oil leakage to tow her car. While repairing the vehicle, a monster attacks him but neither Kathy nor Lizzy note. When they seek Jesse out, they realize that they are not alone in the spot. Further, Kathy learns that monsters do exist. Will they be rescued on time?

Jason tragically lost his young son when their SUV exploded. Now fighting as a soldier in Iraq, the suicide bombings that occur around him on a daily basis constantly remind him of losing his son. An army scientist approaches Jason about an experimental virus that would create a squad of suicide bombers they could use against the enemy. Uncertain if he has already been infected by the virus, Jason must struggle to decipher which explosions are real and which are in his head.